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February 1991

Malignant Melanoma in Human Immunodeficiency Virus Type 2 Infection

Author Affiliations

Department of Dermatology Dermatologische Klinik und Poliklinik der Ludwig-Maximilians Universität München Frauenlobstrasse 9-11 8000 München 2, Federal Republic of Germany

Arch Dermatol. 1991;127(2):266-267. doi:10.1001/archderm.1991.01680020138025

To the Editor.—  Although Kaposi's sarcoma and non-Hodgkin's lymphomas are the most common neoplasms in human immunodeficiency virus (HIV) infection, other neoplasms have been described, such as colorectal cancer, cancer of the lung, and squamous cell carcinoma of the oral and anal mucosa.In recent years, some authors have reported dysplastic nevi and malignant melanoma in patients with HIV infection,1-3 and Rasokat and coworkers3 theoretically estimated a very high incidence of 100 malignant melanomas per 100 000 HIV-infected patients. This article describes a patient with malignant melanoma in HIV-2 infection running a fulminant course.

Report of a Case.—  A 39-year-old homosexual man (the case was reported briefly in a publication concerning HIV-1 and HIV-2 distribution in West Germany4) had a 7-year history of a brown lesion on his back, but was unaware of changes in size or pigmentation. The patient had several homosexual contacts in Europe, North

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