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March 1991

Tumorous Nodules on the Lower Extremities

Author Affiliations

Harvard Medical School, Boston, Mass

Arch Dermatol. 1991;127(3):409-410. doi:10.1001/archderm.1991.01680030129021

REPORT OF A CASE  A 65-year-old man was admitted for surgical excision of extensive cutaneous tumors on the lower extremities, the ninth such operation in 10 years. Indications for surgery included local bleeding from minimal trauma, limitation of motion, and cosmetic disfigurement. Recent medical issues had included chronic intermittent crampy abdominal pain, particularly precipitated by alcohol; episodic flushing, warmth, and palpitations; a history of anaphylaxis associated with the ingestion of aspirin; and gradual weight loss of approximately 11.25 kg (25 lbs) over the preceding 10 years.On examination, the patient was an emaciated elderly man in good spirits. Both lower extremities were covered with spongy, friable, purple-red nodules up to 5 cm in diameter, sparing only the patella region and the soles of the feet (Fig 1). The trunk and upper extremities revealed smaller nodules and reddish-brown plaques (Fig 2) as well as areas of macular telangiectasia (Fig 3).

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