[Skip to Navigation]
March 1991

Therapy of Advanced Melanoma: Pigment Cell

Author Affiliations

Boston, Mass

Arch Dermatol. 1991;127(3):433. doi:10.1001/archderm.1991.01680030159031

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The rising mortality rates for melanoma have stimulated many approaches in research in the attempt to treat this tumor. This monograph presents an up-to-date summary of recent therapeutic considerations in advanced and metastatic melanoma.

Those approaches include surgery, radiotherapy, chemotherapy, immunotherapy, limb perfusion, monoclonal antibody therapy, and metabolic-based treatment. Of the 13 chapters in this monograph, four are devoted to immunotherapy, reflecting the rapid advances that have emerged in this area over the last 5 years. While there is some overlap in these four chapters, they summarize the inherent excitement in this new approach to metastatic melanoma. The chapter by Kirkwood and colleagues on biological-response modifiers is particularly well done.

Of the remaining chapters, the chapter by Kleeberg and colleagues on chemotherapy has a very thoughtful introduction and is one of the best in this monograph. The excellent chapter by Allan and Cornbleet offers many informative tables and a succinct

First Page Preview View Large
First page PDF preview
First page PDF preview
Add or change institution