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The rising mortality rates for melanoma have stimulated many approaches in research in the attempt to treat this tumor. This monograph presents an up-to-date summary of recent therapeutic considerations in advanced and metastatic melanoma.
Those approaches include surgery, radiotherapy, chemotherapy, immunotherapy, limb perfusion, monoclonal antibody therapy, and metabolic-based treatment. Of the 13 chapters in this monograph, four are devoted to immunotherapy, reflecting the rapid advances that have emerged in this area over the last 5 years. While there is some overlap in these four chapters, they summarize the inherent excitement in this new approach to metastatic melanoma. The chapter by Kirkwood and colleagues on biological-response modifiers is particularly well done.
Of the remaining chapters, the chapter by Kleeberg and colleagues on chemotherapy has a very thoughtful introduction and is one of the best in this monograph. The excellent chapter by Allan and Cornbleet offers many informative tables and a succinct
Koh HK. Therapy of Advanced Melanoma: Pigment Cell. Arch Dermatol. 1991;127(3):433. doi:10.1001/archderm.1991.01680030159031
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