To the Editor.
—In "The Cutting Edge" section of the July issue of the Archives, Ledwig and Robinson1 said that melanoacanthoma is "a rare benign variant of seborrheic keratosis." Rare seems to be an inseparable adjective of melanoacanthoma. Pinkus and Mehregan2 emphasize "that this is an extremely rare tumor." Sanderson and Mackie3 refer to it as "a very rare lesion," and Lever and Schaumburg-Lever4 as a "rather rare variant of pigmented seborrheic keratosis." For Maize and Ackerman5 "seborrheic keratoses... are not usually associated with a striking proliferation of melanocytes." But, how rare is melanoacanthoma How many seborrheic keratoses are associated with a striking proliferation of melanocytes?To our knowledge, the only publication where this question stated is that of Sánchez Yus and Simón6 in 1969. These authors stained sections of seborrheic keratosis from nation;in two cases with Masson-Fontana silver impregnation;in two cases fresh tissue
Simón P, Requena L, Yus ES. How Rare Is Melanoacanthoma?. Arch Dermatol. 1991;127(4):583–584. doi:10.1001/archderm.1991.04510010151023
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