• Pachyonychia congenita is an autosomal dominant disorder that usually develops in early infancy. We have observed five patients with the onset of the typical subungual hyperkeratoses of pachyonychia during the teenage years. Leukokeratosis and keratoderma of the palms and soles were associated. The family history of three of the patients suggests that pachyonychia congenita tarda is also inherited in an autosomal dominant manner.
(Arch Dermatol. 1991;127:701-703)
Paller AS, Moore JA, Scher R. Pachyonychia Congenita Tarda: A Late-Onset Form of Pachyonychia Congenita. Arch Dermatol. 1991;127(5):701–703. doi:10.1001/archderm.1991.01680040109013
Dermatology in JAMA: Read the Latest
Customize your JAMA Network experience by selecting one or more topics from the list below.