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May 1991

Pachyonychia Congenita Tarda: A Late-Onset Form of Pachyonychia Congenita

Author Affiliations

From the Departments of Dermatology, The Children's Memorial Hospital of Northwestern University Medical School (Dr Paller) and Rush Medical College (Dr Moore), Chicago, Ill, and Columbia University, New York, NY (Dr Scher).

Arch Dermatol. 1991;127(5):701-703. doi:10.1001/archderm.1991.01680040109013

• Pachyonychia congenita is an autosomal dominant disorder that usually develops in early infancy. We have observed five patients with the onset of the typical subungual hyperkeratoses of pachyonychia during the teenage years. Leukokeratosis and keratoderma of the palms and soles were associated. The family history of three of the patients suggests that pachyonychia congenita tarda is also inherited in an autosomal dominant manner.

(Arch Dermatol. 1991;127:701-703)

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