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May 1991

Psoriasiform Papules in the Acquired Immunodeficiency Syndrome

Author Affiliations

Harvard Medical School and Brigham and Women's Hospital, Boston, Mass

Arch Dermatol. 1991;127(5):725-726. doi:10.1001/archderm.1991.01680040133020

REPORT OF A CASE  A 32-year-old homosexual man was admitted to the hospital with a 5-day history of a pruritic, disseminated, papular eruption associated with fever and cough.The patient was a native of New Orleans, La, but had lived in Boston, Mass, for 3 years. Six months before admission, he had traveled briefly to Houston, Tex. Three years prior to admission, he suffered a cerebrovascular accident associated with cocaine use, leaving him with minor left-sided weakness. Two months before admission, he manifested chronic cutaneous herpes simplex of the buttock, which resolved with oral acyclovir. One month earlier, he was found to be anergic to purified protein derivative and Candida albicans antigen. Three weeks before admission, he had had a left focal motor seizure, and phenytoin therapy was begun. An unspecified rash developed after 2 days; phenobarbital therapy was substituted for the phenytoin therapy, and the eruption resolved.Ten days

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