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July 1991

Cutaneous T-Cell Lymphoma Associated With the Acquired Immunodeficiency Syndrome

Author Affiliations

From the Department of Dermatology and Cutaneous Surgery, University of Miami (Fla) School of Medicine.

Arch Dermatol. 1991;127(7):1020-1022. doi:10.1001/archderm.1991.01680060094011

• Four cases of T-cell lymphoma occurring in the setting of the acquired immunodeficiency syndrome (AIDS) have been reported previously. We describe a 46-year-old man with AIDS in whom a cutaneous T-cell lymphoma with lymph node involvement developed. Immunohistochemical staining of the skin revealed the lymphoid infiltrate to be CD3+, CD4-, CD8-, and T-cell antigen receptor alpha/beta positive. Coinfection with human T-cell lymphotropic virus type I was not detected by polymerase chain reaction. Human immunodeficiency virus infection may have contributed to the development of this patient's lymphoma. This case represents the rare occurrence of cutaneous T-cell lymphoma and AIDS.

(Arch Dermatol. 1991;127:1020-1022)

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