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July 1991

Congenital Basal Cell Carcinoma

Arch Dermatol. 1991;127(7):1066-1067. doi:10.1001/archderm.1991.01680060142029

To the Editor.—  Basal cell carcinoma (BCC) is an uncommon skin tumor in prepubertal children, and is usually associated with basal cell nevus syndrome, Bazex syndrome, or xeroderma pigmentosum. Basal cell tumors that develop within a nevus sebaceous rarely appear before puberty.1 We report a biopsy-proven BCC that occurred in an otherwise healthy 6-year-old white boy; the lesion was initially noticed at birth as a small skin-colored papule at the left supraclavicular area. The lesion remained relatively unchanged and was excised 6 years later at the mother's request. Basal cell carcinoma was not suspected clinically. Histologic sections revealed solid masses and strands of basaloid cells, several areas of which formed glandlike structures (Figure). The lumina were filled with amorphous, somewhat eosinophilic material. There was also a mild fibrous reaction of the stroma, vascular dilatation, and scattered perivascular infiltrates in the dermis. There was no evidence of associated nevus