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August 1991

Isolation of Human Immunodeficiency Virus Type 1 in Cutaneous Blister Fluid

Author Affiliations

From the Departments of Dermatology (Drs Supapannachart and Breneman), Internal Medicine (Dr Linnemann), and Pathology and Laboratory Medicine (Dr Linnemann), University of Cincinnati (Ohio) College of Medicine.

Arch Dermatol. 1991;127(8):1198-1200. doi:10.1001/archderm.1991.01680070098013

• The human immunodeficiency virus type 1 (HIV-1) has been isolated from a number of body fluids, including semen, tears, cerebrospinal fluid, saliva, breast milk, alveolar fluid, and vaginal fluid, but it has not been isolated from fluidcontaining skin lesions. We report the isolation of HIV-1 from cutaneous blister fluid in a patient with concomitant HIV-1 infection and porphyria cutanea tarda. Although transmission of HIV-1 through casual contact has not been reported, appropriate precautions should be taken to avoid direct contact with cutaneous fluid-containing lesions in HIV-1-positive patients.

(Arch Dermatol. 1991;127:1198-1200)