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October 1991

Histologic Evaluation of Nail Clippings for Diagnosing Onychomycosis

Author Affiliations

From the Departments of Dermatology (Drs Suarez, Silvers, and Scher) and Pathology (Dr Silvers), College of Physicians and Surgeons of Columbia University, and Dermatology Associates, PC (Drs Pearlstein and Auerbach), New York, NY.

Arch Dermatol. 1991;127(10):1517-1519. doi:10.1001/archderm.1991.01680090081008

• Nail clippings from patients suspected of having onychomycosis were processed for histologic evaluation in the same manner as routine skin with the addition of a chitinsoftening solution prior to processing. The sections were stained by the periodic acid—Schiff method and examined for fungal hyphae. The results were compared with the results of fungal cultures from the same nail. Our findings indicate that routine histopathologic analysis of the nail plate alone is a useful complementary method to fungal culture for diagnosing onychomycosis.

(Arch Dermatol. 1991;127:1517-1519)

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