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October 1991

Cutaneous Manifestations of Human Immunodeficiency Virus Infection: Part II

Author Affiliations

From the Division of Dermatology, New England Deaconess Hospital, and Department of Dermatology, Harvard Medical School, Boston, Mass.

Arch Dermatol. 1991;127(10):1549-1558. doi:10.1001/archderm.1991.01680090113015

Part I appeared in the September issue of the Archives.

Bacterial Infections 

Staphylococcus aureus Infection.—  Staphylococcus aureus is the most common pathogen in cutaneous and systemic bacterial infections occurring in HIV-infected individuals. Staphylococcus aureus colonizes the nose initially and may subsequently infect various sites. In both asymptomatic and symptomatic HIV-infected individuals, the S aureus nasal carriage rate is twice that of control groups. Staphylococcus aureus may also be locally invasive at the carriage site causing nasal abscess.The incidence of S aureus infection in HIV-infected patients is high, causing significant morbidity and mortality. In a study of 46 adult patients with AIDS, autopsy examination revealed that 83% had had a bacterial (nonmycobacterial) infection at some time during the course of their illness, of which 54% had been caused by S aureus. Nosocomial infections occur in HIV-infected patients at the rate of 3.46 per thousand hospital days compared with the rate

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