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October 1991

Childhood Bullous Pemphigoid

Author Affiliations

Clinic of Dermatology Hôpital Cantonal Universitaire 1211 Geneva 4, Switzerland

Arch Dermatol. 1991;127(10):1586. doi:10.1001/archderm.1991.01680090152025

To the Editor.—  We enjoyed the comprehensive review on childhood bullous pemphigoid (BP) by Nemeth et al1 in the March 1991 issue of the Archives, and we would like to draw the authors' attention to one additional case they did not mention2,3 that we think is of interest. A 3-month-old boy had lesions localized to his feet; this, indeed, appears to be a striking clinical feature of BP at this age. The bullous eruption dramatically responded to sulfapyridine therapy (120 mg/d) for 6 weeks. No recurrence has been seen after 3 years of follow-up. The mother has had, during pregnancy, an eruption thought to be the "pruritic urticarial papules and plaques of pregnancy," but, for the reasons discussed elsewhere,3 we could not exclude herpes gestationis; no circulating antibodies in the mother's serum were detectable by Western blotting 3 months after delivery.2 Therefore, we could not establish

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