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March 1992

Sudden Vegetation of the Mouth

Arch Dermatol. 1992;128(3):401-402. doi:10.1001/archderm.1992.01680130115018

REPORT OF A CASE  Two months before presentation, an eroded lesion localized in the left retromolar area developed in a 26-year-old woman. Mild pain also developed. Her history revealed that, before the lesion appeared, she was treated for 1.5 months for hydrarthrosis of the left knee with a combination of various oral anti-inflammatory agents. About 10 days after discontinuing medication for hydrarthrosis, the above-mentioned primary lesion appeared.The patient was treated with oral acyclovir, phosphomycin, and spiramycin and chlorhexidine mouth rinses on a long-term basis, but no improvement was seen in her "stomatitis."On the contrary, the lesion progressed extensively and the clinical features changed. At the time of our examination, numerous scattered or, sometimes, coalescent 2- to 3-mm yellow pustules were observed. The surrounding mucosa was erythematous and moderately vegetating (Fig 1).The lesions were localized to the attached gingiva and the labial and buccal mucosa of the left

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