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June 1992

Association of Granuloma Annulare With Sarcoidosis

Author Affiliations

Department of Medicine Division of Immunology and Rheumatology; Department of Dermatology Stanford University School of Medicine Stanford. CA 94305

Arch Dermatol. 1992;128(6):855-856. doi:10.1001/archderm.1992.01680160145029

To the Editor.—  Granuloma annulare (GA) and sarcoidosis represent well-described granulomatous disorders of unclear pathogenesis. Although generally considered individually distinct, GA in association with sarcoidosis has been described in three prior reports.1-3 We report another case of sarcoidosis that presented with GA. The coexistence of GA and sarcoidosis may reflect a shared underlying mechanism of pathogenesis.

Report of a Case.—  The patient, a 57-year-old man, was admitted with fever, night sweats, malaise, and arthralgias of 2 weeks' duration. Previously he had been in excellent health. Physical examination was remarkable for tenderness and effusion with overlying erythema involving the right wrist and the ankles bilaterally. Multiple asymptomatic, erythematous papules, some discrete and others coalescing into annular plaques, were present on the shoulders, the thenar eminence, and the dorsal aspect of his hands and feet. The skin lesions blanched with diascopy, and they appeared concurrently with his systemic symptoms. Laboratory evaluation