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June 1992

Discrete Papular Mucinosis Responding to Intralesional and Topical Steroids

Author Affiliations

Department of Dermatology Bristol Royal Infirmary Bristol, England BS2 8HW

Arch Dermatol. 1992;128(6):857-858. doi:10.1001/archderm.1992.01680160147031

To the Editor.—  The treatment of papular mucinosis is usually unsatisfactory, but we describe here a patient with discrete papular mucinosis whose lesions responded to therapy with intralesional and topical steroids.

Report of a Case.—  A 32-year-old man presented with multiple discrete nodules over his limbs and chest. The patient reported that he had these nodules for 4 years. The lesions had appeared within a few months and then remained unchanged.Findings from his physical examination revealed numerous skincolored papules, mainly over the upper limbs (Fig 1), with one or two lesions over the back and legs.A skin biopsy specimen of one papule from the arm showed a loose, irregular proliferation of spindle cells in the dermis, in places following a storiform pattern (Fig 2). Irregular bundles of collagen and a moderate perivascular infiltrate, consisting mostly of plasma cells, were seen. Sections of the papular lesion were stained with

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