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July 1992

Becker's Nevus and Ipsilateral Breast Hypoplasia Androgen-Receptor Study in Two Patients

Author Affiliations

Department of Dermatology; Department of Hormonology Hospital Clinic i Provincial Casanovas 143, 08036 Barcelona, Spain

Arch Dermatol. 1992;128(7):992-993. doi:10.1001/archderm.1992.01680170128025

To the Editor.—  Becker's nevus, a unilateral hairy hyperpigmented cutaneous hamartoma, which usually appears in adolescence, has been described along with cutaneous (epidermal and dermal nevus) and structural abnormalities (skeletal changes and breast hypoplasia).1 Its association with homolateral breast hypoplasia has been reported rarely. Only four other cases have been reported in the literature.1-4We report two new cases of this association, together with the results of androgen-receptor levels of pigmented and contralateral nonpigmented skin.

Report of Cases.—Case 1.—  A 16-year-old girl presented to our service. When the patient was 3 years old, an asymptomatic, progressive, and mild hypertrichotic hyperpigmentation was noticed on the right side of her body by her mother. Hypoplasia on the child's right breast became noticeable in adolescence. The physical examination revealed a homogeneous, macular, light-brown hyperpigmentation of the right side of the trunk and the right shoulder. The hyperpigmentation was well defined,

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