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July 1992

Papular Mucinosis and Human Immunodeficiency Virus Infection

Author Affiliations

Department of Dermatology, 4M70 San Francisco General Hospital 1001 Potrero St San Francisco, CA 94110

Arch Dermatol. 1992;128(7):995-996. doi:10.1001/archderm.1992.01680170131028

To the Editor.—  Most cutaneous disorders associated with the human immunodeficiency virus (HIV) infection are of infectious or neoplastic origin. Dermal connective-tissue processes have received only passing mention.1,2 We describe two patients with symptomatic HIV-infection and papular mucinosis (lichen myxedematosus).

Report of Cases.—Case 1.—  A 35-year-old homosexual man with symptomatic HIV infection had been found to be HIV seropositive in February 1984. In October 1990, he gave an 8-month history of an asymptomatic generalized papular eruption on his trunk and thighs. The patient denied L-tryptophan ingestion.Findings from his physical examination revealed multiple 2- to 4-mm flesh-colored papules concentrated on his trunk and thighs. They were firm and smooth on their surface (Fig 1). There was no induration or thickening of the affected skin. Ten months later, the lesions were essentially unchanged. None of the papules had resolved, and there were no newly affected areas. The lesions showed no tendency to become confluent, and sclerodermoid changes were absent.

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