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September 1992

A Bullous Eruption in a Young Woman

Author Affiliations

Department of Dermatology, The Johns Hopkins University, Baltimore, Md

Arch Dermatol. 1992;128(9):1267-1268. doi:10.1001/archderm.1992.01680190125019

REPORT OF A CASE  A 29-year-old black woman was referred to The Johns Hopkins University Dermatology Service, Baltimore, Md, for evaluation of a blistering eruption of several weeks' duration involving her face, trunk, and extremities.One year before referral, she underwent a laparoscopy and tubuloplasty; subsequent to this, a recurrent weepy umbilical eruption developed that waxed and waned independent of multiple courses of antibiotics. Three months before her referral, scattered hyperpigmented pruritic papules developed on her right leg. These were thought to represent insect bite reactions, and she was placed on a 3-week tapering course of prednisone with minimal improvement. Shortly thereafter, generalized pruritus developed followed by a cutaneous blistering eruption involving the face, neck, trunk, and extremities.Her medical history was remarkable for one uncomplicated pregnancy. She was not receiving therapy with oral contraceptives, estrogen, or progesterone.Her physical examination showed generalized urticarialpapules and plaques, many of which

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