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September 1992

Hypopigmented Macules

Author Affiliations

Department of Dermatology, New York (NY) University School of Medicine

Arch Dermatol. 1992;128(9):1269-1270. doi:10.1001/archderm.1992.01680190127020

REPORT OF A CASE  A 68-year-old black woman complained of an increasing number of "white spots" on her arms and legs. These spots began appearing about 7 months earlier and were asymptomatic.The physical examination revealed numerous hypopigmented macules on her thighs (Figs 1 and 2). Lesions were also present on her upper extremities and abdomen, but in lesser numbers. Erythema, scaling, or atrophy was not appreciable in any of the lesions. Loss of sensation to light touch was absent. A potassium hydroxide preparation for fungal elements was negative. Examination under Wood's light demonstrated that the lesions were hypopigmented, not depigmented. Lymphadenopathy, hepatomegaly, or organomegaly was absent. A complete blood cell count, SMA-12, and urinalysis showed normal findings.A biopsy specimen of one of the hypopigmented lesions was obtained. A representative section stained with hematoxylineosin is shown in Fig 3.What is your diagnosis?

DIAGNOSIS:  Hypopigmented mycosis fungoides (MF).

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