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September 1992

Severe Phototoxic Burn Following Celery Ingestion-Reply

Author Affiliations

Department of Dermatology Lund University S-214 01 Malmö, Sweden

Arch Dermatol. 1992;128(9):1277. doi:10.1001/archderm.1992.01680190137024

In Reply.—  Drs Dijkstra and Chang have noted a calculation error in the report in the October 1990 issue of the Archives.1 I can only confirm that the amount of methoxsalen (8-methoxypsoralen)—equivalent psoralens in the extract would correspond to a total dose of about 22.5 mg in the particular piece of celery root analyzed.Since the purpose of the evaluation was to demonstrate that clinically relevant psoralen amounts may be ingested under special circumstances, I believe that the conclusions of the report still hold true.In addition, it is important to remember that the celery root we analyzed was obtained from the market 1 week after the patient bought the photosensitizing piece, and the results can only give indirect evidence of the psoralen levels of the actual piece of celery.In fact, little is known about the variation in psoralen content between different varieties of celery and how the conditions under