REPORT OF A CASE
A 12-year-old Hispanic girl presented with asymptomatic linear tumors on the left lower flank of 3 to 4 years' duration. Before the tumors appeared, she noted flat brown spots in the same area. She was otherwise in good health.The physical examination revealed soft, rubbery tan-to- yellow papules and nodules coalescing to form cerebriform plaques in a zosteriform distribution limited to the left lower flank (Fig 1). A small amount of increased terminal hair was also present.A biopsy specimen was taken from the medial portion of the lesion and stained with hematoxylin-eosin (Figs 2 and 3).What is your diagnosis?
Nevus lipomatosus cutaneus superficialis (Hoffmann-Zurhelle).
The epidermis was papillomatous with occasional follicular plugs. There was a slight increase in the vasculature in the upper dermis with a scattered lymphocytic infiltrate. The predominant finding was the ectopic, mature collections of adipose tissue throughout most of the dermis.
Steven P. Eyre, Adelaide A. Hebert, Ronald P. Rapini. Rubbery Zosteriform Nodules on the Back. Arch Dermatol. 1992;128(10):1395–1396. doi:10.1001/archderm.1992.01680200105018