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October 1992

Immunofluorescence Findings in Lichen Planopilaris: A Contrasting Experience

Author Affiliations

USA; USA; USA; Dermatology Service Brook Army Medical Center Fort Sam Houston, TX 78234; USAF; Wilford Hall Air Force Medical Center Lackland Air Force Base, TX 78236

Arch Dermatol. 1992;128(10):1405-1406. doi:10.1001/archderm.1992.01680200117024

To the Editor.—  We read with interest the article by Ioannides and Bystryn1 in the February 1992 issue of the Archives on the immunofluorescence abnormalities in lichen planopilaris (LPP). They described seven patients with linear deposits of Ig restricted to the basement membrane zone of hair follicles and no staining of ovoid bodies.We report our direct immunofluorescence findings (DIF) in seven patients with LPP of the scalp.

Patients and Methods.—  We studied seven patients with LPP, six women and one man. Their ages ranged from 29 to 73 years (mean, 40.7 years). The duration of the disease (from onset to biopsy) ranged from 3.5 months to 5 years (mean, 1.6 years). The scalp was involved in all patients, with one patient also showing lesions consistent with lichen planus on the lower back.All patients presented with scarring alopecia of the scalp associated with small, follicular, violaceous to dusky

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