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June 1993

Vulvar Lichen Planus Treated With Topical Cyclosporine

Author Affiliations

Servicio de Dermatología Hospital "12 de Octubre" Carretera de Andalucía Km 5.4 28041 Madrid, Spain

Arch Dermatol. 1993;129(6):794. doi:10.1001/archderm.1993.01680270138030

To the Editor.—  Vulvar lichen planus often results in pain, burning, and pruritus, causing the patient great discomfort. Treatment is often frustrating and unsuccessful.1 Cyclosporine has been shown to be efficacious topically in the treatment of oral lichen planus.2,3 We report a case of vulvar lichen planus and its successful management with topical cyclosporine.

Report of a Case.—  A 58-year-old white woman with a history of mitral valve stenosis (treated with commissurotomy in 1979) and chronic active hepatitis C was first seen in September 1989 for evaluation of purpuric vulvar lesions of 1 year's duration. Lesions were extremely pruritic with a burning sensation. At that time, medication consisted of digoxin (0.25 mg/d), amiloride (5 mg/d), and hydroxyclorothiazide (50 mg/d).On physical examination, hemorrhagic plaques were found in the labia minora and the clitorial hood. Erosions were present in the upper vestibule with partial atrophy of the labia minora.

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