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July 1993

Neutrophilic Sebaceous Adenitis

Author Affiliations

Department of Dermatology The Ronald O. Perelman Department of Dermatology New York University Medical Center 530 First Ave New York, NY 10016

Arch Dermatol. 1993;129(7):910-911. doi:10.1001/archderm.1993.01680280100027

To the Editor.—  We observed a patient with circinate plaques of the face characterized histologically by inflammation of the sebaceous glands. We term this disorder neutrophilic sebaceous adenitis. Its cause is unknown.

Report of a Case.—  A previously healthy 18-year-old white man presented with erythematous and indurated circinate plaques of the face that had violaceous, elevated borders (Fig 1). The lesions began 1 month after a 1-week course of cephalexin taken for bronchitis. No other mucocutaneous or systemic findings were noted. The patient denied risk factors for the human immunodeficiency virus. Treatment with clotrimazole and betamethasone dipropionate cream over 3 weeks led to partial clearing; however, the process recurred several times in the next few months. Empiric treatment with tetracycline and griseofulvin was ineffective. Systemic steroid therapy (prednisone [40 mg/d for 1 week]) was begun, and the lesions began clearing. Follow-up at 10 months revealed complete resolution without scarring.Laboratory

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