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August 1993

Confluent and Reticulated Papillomatosis: Treatment With Etretinate

Arch Dermatol. 1993;129(8):961-963. doi:10.1001/archderm.1993.01680290033005


Case 1  A 26-year-old obese Saudi Arabian man reported to the dermatology clinic with an itchy skin eruption of several years' duration. The patient's condition had been diagnosed as tinea versicolor and had failed to respond to several months of treatment with topical 1% clotrimazole cream or 2.5% selenium sulfide lotion. His family history was negative for any similar disease.On dermatologic examination, hyperpigmented, reticulated scaly patches and plaques were present on the neck, back, sternal region, and antecubital fossae. The neck, axillae, and groin displayed lesions of acanthosis nigricans. On Wood's light examination only a faint yellow fluorescence could be detected. The potassium hydroxide smear was negative. The results of laboratory studies (complete blood cell count, urinalysis, serum electrolyte levels, renal and liver function tests, and serum cholesterol and triglyceride levels) were within normal limits.He was treated with ketoconazole (200 mg twice a day) for