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September 1993

The Role of Magnetic Resonance Imaging in the Diagnostic Evaluation of Dermatomyositis

Author Affiliations

USA; USA; Walter Reed Army Medical Center, Washington, DC

Arch Dermatol. 1993;129(9):1104-1106. doi:10.1001/archderm.1993.01680300032006

REPORT OF A CASE  A 50-year-old white woman presented to our clinic for evaluation of a photosensitive skin eruption of 15 months' duration. The patient described a burning sensation after sun exposure, followed by persistent erythema. She practiced strict sun avoidance for several months before presenting to a local dermatologist. An evaluation revealed mild diffuse nonscarring alopecia, a positive antinuclear antibody titer (1:320), and a negative SSA/SSB titer. Laboratory studies revealed normal creatinine phosphokinase and aldolase values and a white blood cell count of 26×109/L. A diagnosis of systemic lupus erythematosus was rendered, and treatment with hydroxychloroquine sulfate (Plaquenil) (200 mg twice daily) was initiated. The patient's eruption progressed, and mild dysphagia developed, with a 4.5-kg weight loss over the following 3 months. Her history revealed that she had undergone a partial colectomy followed by chemotherapy with fluorouracil and local irradiation for colon cancer (classification, Duke's B) 2

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