[Skip to Navigation]
Article
February 1994

Diffuse Petechial Pustular Lesions in a Newborn

Author Affiliations

USA; USN; USN; USA; Walter Reed Army Institute of Research, Washington, DC (Dr Smith); National Naval Medical Center, Washington, DC (Dr Yeager); Armed Forces Institute of Pathology, Washington, DC (Dr Skelton); and AIDS Registry, Washington, DC (Dr Angritt)

Arch Dermatol. 1994;130(2):248. doi:10.1001/archderm.1994.01690020117021
Abstract

REPORT OF A CASE  The patient's mother presented febrile and in spontaneous labor in the second trimester of her pregnancy. The mother was positive for the human immunodeficiency virus (HIV) and had a history of drug abuse. The neonate was alive at birth with a diffuse papular, petechial, pustular eruption (Figure 1). Blood cultures were performed and the patient died soon thereafter. Blood cultures subsequently were positive for gram-positive coccobacilli.On autopsy, the placenta showed diffuse hematogenous placentitis with acute necrotizing villitis, acute intervillitis, and gram-positive coccobacilli demonstrated with Brown-Hopps stain. The patient's lungs showed acute bronchopneumonia with gram-positive coccobacilli. Examination of the skin revealed patchy involvement of the dermis with gram-positive coccobacilli. Within the area of involvement was a mononuclear infiltrate with focal areas of necrobiosis. In addition, groups of organisms could be found within the epidermis in association with spongiosis and exocytosis of mononuclear cells (Figure 2). Other

Add or change institution
×