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May 1994

Postzoster Cutaneous Pseudolymphoma

Author Affiliations

Department of Dermatology Universitario San Carlos Zurbano 25 28010 Madrid, Spain

Arch Dermatol. 1994;130(5):661-663. doi:10.1001/archderm.1994.01690050131026

Pseudolymphomas are defined as localized, reactive, inflammatory processes of the skin that clinically and histologically may resemble malignant lymphomas.1

We report pseudolymphoma appearing in the scar tissue of a previous herpes zoster in a patient with chronic lymphocytic leukemia with documentation of the clinical, histologic, and immunocytochemical findings.

Report of a Case.  A 45-year-old woman had a 2-year history of chronic lymphocytic leukemia of the monoclonal B-cell type that was treated with chlorambucil and prednisolone.She presented with an erythematoviolaceous papular and nodular eruption distributed in the left D4-D5 dermatome (Figure 1). Lesions occurred at the site of scars relating to an episode of herpes zoster 2 months previously for which she had required treatment with oral acyclovir.Histologically, there was a dense nodular infiltrate present mainly in the upper part of the dermis and extending to the lower dermis. Both the epidermis and the papillary dermis were uninvolved.

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