Pseudolymphomas are defined as localized, reactive, inflammatory processes of the skin that clinically and histologically may resemble malignant lymphomas.1
We report pseudolymphoma appearing in the scar tissue of a previous herpes zoster in a patient with chronic lymphocytic leukemia with documentation of the clinical, histologic, and immunocytochemical findings.
Report of a Case.
A 45-year-old woman had a 2-year history of chronic lymphocytic leukemia of the monoclonal B-cell type that was treated with chlorambucil and prednisolone.She presented with an erythematoviolaceous papular and nodular eruption distributed in the left D4-D5 dermatome (Figure 1). Lesions occurred at the site of scars relating to an episode of herpes zoster 2 months previously for which she had required treatment with oral acyclovir.Histologically, there was a dense nodular infiltrate present mainly in the upper part of the dermis and extending to the lower dermis. Both the epidermis and the papillary dermis were uninvolved.
Roo E, Villegas C, Lopez-Bran E, Jimenez E, Valle P, Sanchez-Yus E. Postzoster Cutaneous Pseudolymphoma. Arch Dermatol. 1994;130(5):661–663. doi:10.1001/archderm.1994.01690050131026
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.