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July 1994

Treatment of Pretibial Mucinosis With Gradient Pneumatic Compression

Author Affiliations

Roxborough Memorial Hospital, Philadelphia, Pa

Arch Dermatol. 1994;130(7):842-844. doi:10.1001/archderm.1994.01690070032004

REPORT OF CASES  An 83-year-old white man presented with multiple flesh-colored-to-erythematous indurated nodules and plaques of both anterior tibial areas (Figure 1 and Figure 2). Nonpitting edema was also apparent. By history, the condition first began approximately 7 years ago and continued to progress in severity. Because of continuous drainage of fluid from his left lower leg, the patient would wrap this area with gauze or handkerchiefs; within several hours these would be soaked, necessitating new application. Recent medical history was negative for significant renal, hepatic, and cardiac disease, and he could not recall diagnosis or treatment of thyroid disease. The patient's only medication was hydrochlorthiazide for control of mild hypertension.A shave biopsy specimen of a leg nodule revealed a thickened dermis with a marked increase in spindle mucoblasts and mucin deposition, as demonstrated by colloidal iron staining. Laboratory studies including triiodothyronine, thyroxine, and thyroid stimulating hormone demonstrated no