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February 1995

Long-standing Subcutaneous Nodule in a Young Woman

Author Affiliations

Baylor College of Medicine and St Joseph Hospital, Houston, Tex

Arch Dermatol. 1995;131(2):215-216. doi:10.1001/archderm.1995.01690140099018

REPORT OF A CASE  A 33-year-old woman presented with a 2- to 3-cm subcutaneous nodule in the medial aspect of her right arm. The nodule was of many years' duration. The patient noted a new nodule distal to the larger lesion that was of 1 to 2 years' duration, occurring after pregnancy. On physical examination, a 2.5 ×3.5-cm erythematous, slightly scaly plaque was found in the medial aspect of the right arm. A 1-cm pink nodule was seen approximately 1 cm distal to the larger lesion (Figure 1). A 4-mm punch biopsy specimen was obtained (Figure 2 through Figure 4).What is your diagnosis?

DIAGNOSIS:  Plexiform fibrohistiocytic tumor.

HISTOPATHOLOGIC FINDINGS  A dermal nodule containing a concentric fibroblastic proliferation with hyalinized collagen was found frequently surrounding nerves and containing a patchy mononuclear infiltrate (Figure 2 and Figure 3). Most spindle cells and many