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February 1995

Diascopy, the Lips, and Vitiligo

Author Affiliations

Department of Dermatology Sassoon General Hospital and B. J. Medical College Pune 411 001, India

Pune, India

Arch Dermatol. 1995;131(2):228-229. doi:10.1001/archderm.1995.01690140114027

Vitiligo macules on the skin are easily diagnosed by their uniform chalk-white color and their convex margins, sometimes bordered by a trichrome.1

The deep crimson hue of the lips effectively camouflages these characteristic features, making vitiligo macules difficult to discern over the lips and obscuring the distinction

Figure 1.  Top, Probable vitiligo macules obscured by the crimson hue of the lips. Bottom, Diascopy reveals uniformly white amelanotic macules with sharp convex margins and confirms the diagnosis of vitiligo. Invisible brown shades of melanin are also revealed. between amelanotic vitiligo macules and hypomelanotic postinflammatory lip lesions. We found diascopy to be an effective means of resolving this dilemma.We examined 105 randomly selected patients who either sought treatment for hypochromic lip lesions or who presented with other dermatologic lesions and coincidentally had dischromic macules over the lips.We examined the lips of each individual through a glass slide that was

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