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March 1995

Encephalitis Associated With Cat Scratch Disease—Broward and Palm Beach Counties, Florida, 1994

Arch Dermatol. 1995;131(3):254-255. doi:10.1001/archderm.1995.01690150016002

On August 14, 1994, the Broward County Public Health Unit of the Florida Department of Health and Rehabilitative Services was notified of three children from Pompano Beach who were hospitalized with encephalitis attributed to cat scratch disease (CSD). All three children (aged 5, 6, and 11 years) were previously healthy and had no histories of seizure disorders or diagnoses of CSD. This report summarizes the investigation of these cases.

On August 12 and 13, during a 26-hour period, each child entered the emergency department of the same hospital with sudden onset of generalized seizures, coma, and respiratory depression requiring intubation and assisted ventilation. Two of the children had focal lymphadenopathy (axillary and epitrochlear) on admission; cervical lymphadenopathy developed in the third child during hospitalization. Clinical examinations and laboratory tests ruled out some causes of encephalopathy, including viral infections (e.g., herpes simplex and arboviruses), metabolic disorders, and toxic ingestions.

On September

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