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May 1995

Facial Papules in a Child

Author Affiliations

Wayne State University School of Medicine, Detroit, Mich

Arch Dermatol. 1995;131(5):613-614. doi:10.1001/archderm.1995.01690170115020

REPORT OF A CASE  A 19-month-old Albanian girl developed yellow-red papules in both eyelids at age 6 months. Over the past year, new lesions developed on her head and upper trunk. She was asymptomatic and otherwise healthy.The examination revealed multiple scattered 2- to 3-mm yellow-red papules over the scalp and face (Figure 1). A few were present on her upper chest. A complete blood cell count, serum protein electrophoresis, and chemistry panels were normal. Bone marrow aspirate, skeletal survey, chest radiograph, and computed tomographic scan were normal.Histologic findings from a typical lesion are shown (Figure 2). Special stains for CD1 and S100 were positive in a few dermal cells; HLA-DR was strongly positive. Electron microscopy was performed (Figure 3 and Figure 4).What is your diagnosis?

DIAGNOSIS:  Benign cephalic histiocytosis.

HISTOPATHOLOGIC FINDINGS  The epidermis was slightly atrophic. The dermis contained large histiocytic cells with ground-glass cytoplasm, a few multinucleated giant cells,

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