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Psoriasis provides an up-to-date, very comprehensive coverage of the basic science and clinical aspects of psoriasis. The proportion of the book devoted to the basic science aspect of the disease compared with the clinical aspect is roughly on the order of 1 to 2. Even though a lot of the basic science material may be a little more than what the average clinician would like, this section is surprisingly well written and understandable, even for a clinician, since information with regard to new developments is clearly categorized by different subtopics, such as cytokines, plasminogen activator enzymes, oncogenes, fibroblasts, and chemotactic factors. Moreover, each author presents a working model of the pathogenesis of psoriasis with respect to the particular area of investigation discussed rather than simply presenting a laundry list of new observations. This makes the new and old information in the basic science arena much more comprehensible. Some of the