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November 1995

Sporotrichoid Nodules in an Immunocompromised Host

Author Affiliations

Yale University School of Medicine, New Haven, Conn

Arch Dermatol. 1995;131(11):1331-1332. doi:10.1001/archderm.1995.01690230111020

REPORT OF A CASE  A 41-year-old white man, who had a relapse of acute lymphocytic leukemia, was treated with cytarabine, mitoxantrone, and etoposide. Ten days later, he became febrile while neutropenic and was treated with fluconazole, broad-spectrum antibiotics, and granulocyte macrophage colony-stimulating factor. He complained of leftsided facial pain; a sinus series showed opacification of the left maxillary sinus. A biopsy specimen of the sinus showed changes of chronic inflammation. Cultures yielded only Staphylococcus epidermidis. Two weeks later, a 2-cm red nodule was noted on the left forearm and a smaller

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