The WORD cosmeceuticals was coined nearly 10 years ago1 by Albert M. Kligman, MD, PhD, professor emeritus of dermatology, the University of Pennsylvania, Philadelphia, a man who during his career has repeatedly crystalized issues and opportunities within dermatology. The immediate acceptance and subsequent widespread usage of this term and its variants speak to the legitimacy of a product category intermediate between cosmetics and pharmaceuticals.2,3 Nevertheless, regulatory agencies have not yet formally recognized cosmeceuticals, despite a rapid proliferation of "cosmetic" products that have a documented and intended pharmaceutical activity and a dermatologic knowledge base that renders obsolete earlier distinctions between cosmetics and drugs. The following paragraphs review current product realities in the hope of motivating responsible persons and organizations in academe, industry, and government to confront the need for rational definitions and regulatory procedures related to skin care products in the 21st century. We include a general proposal as
Vermeer BJ, Gilchrest BA, Vermeer, Friedel SL. CosmeceuticalsA Proposal for Rational Definition, Evaluation, and Regulation. Arch Dermatol. 1996;132(3):337–340. doi:10.1001/archderm.1996.03890270113017
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