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August 1996

Early Detection of Melanoma Metastasis Using Fludeoxyglucose F 18 Positron Emission Tomography

Author Affiliations

University Hospital, Zurich, Switzerland

Arch Dermatol. 1996;132(8):875-876. doi:10.1001/archderm.1996.03890320023003

REPORT OF A CASE  A 48-year-old man consulted an otorhinolaryngologist because of recurrent nasal bleeding. A biopsy specimen revealed a melanoma of the left nasal cavity. A computed tomographic (CT) scan showed invasion of the left maxillary and ethmoidal sinuses. The left nasal cavity, the sinuses, and the left upper jaw were partly excised, but the primary tumor could not be removed entirely. Over a 6-month period the patient decided to undergo homeopathic treatment only. A subsequent CT scan revealed another parapharyngeal metastasis adjacent to the primary incompletely excised tumor. The parapharyngeal tumor could be excised only partially. Because of the limitations in achieving a surgical cure, the patient received 6 cycles of a combined chemoimmunotherapy for 6 months (dacarbazine [DTIC, Dome, 850 mg/m2], interferon alfa [ Intron A, first week, 106 U/d for 3 doses; third through sixth weeks, 106 U, 3 times a week for 3

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