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April 1997

Acral Peeling Skin Syndrome

Author Affiliations

Department of Dermatology Henry Ford Hospital 2799 W Grand Blvd Detroit, MI 48202


Arch Dermatol. 1997;133(4):535-536. doi:10.1001/archderm.1997.03890400141031

A young man presented to our department with a lifelong history of localized peeling skin of his acral surfaces, especially after exposure to heat, humidity, and/or friction. A histological examination revealed a split above the granular layer without inflammatory response. Only a few reports of peeling skin syndrome have been published and they all describe widespread peeling. Peeling skin syndrome localized to the acral surfaces represents a new variant.

Report of a Case.  A 34-year-old white man was referred to us for possible epidermolysis bullosa. He reported a lifelong history of peeling skin, mainly on both surfaces of his hands and feet, that worsened with exposure to water, perspiration, heat, or friction. Rarely, peeling would occur higher up on his arms and legs. He also reported discreet areas that were callused and pruritic. After soaking his hands and feet in water for 15 minutes and lightly rubbing the skin, he