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April 1997

Globulelike Dermoscopic Structures in Pigmented Seborrheic Keratosis

Author Affiliations

New York

Ronald O. Perelman Department of Dermatology New York University Medical Center 550 First Ave New York, NY 10016

Plantation, Fla

New York

Arch Dermatol. 1997;133(4):540-541. doi:10.1001/archderm.1997.03890400146036

Dermoscopy (also known as dermatoscopy, diascopy, epiluminescent microscopy, and surface microscopy) combines oil immersion with standard magnifying optics to permit in vivo visualization of features of pigmented melanocytic neoplasms that are not discernible by examination with the naked eye. Dermoscopy is being used to assist in clinically differentiating melanoma from its benign simulators. The use of dermoscopy can increase the diagnostic accuracy of pigmented lesions.1,2

More than 100 features have been described using dermoscopy.3-5 Globules, one of the structural components, are typically found in melanocytic neoplasms. According to their color, size, shape, and distribution, globules are suggestive of common melanocytic nevus, congenital nevus, Spitz nevus, dysplastic nevus, and malignant melanoma.3-5 Histologically, globules correspond to superficial nests of melanin-containing melanocytes in the papillary dermis6 and maybe in the lower portion of the epidermis.3,5

We report that seborrheic keratoses also show globulelike structures on dermoscopy. We have