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June 1997

The Histopathology of Closed and Open Comedones of Favre-Racouchot Disease

Author Affiliations

From the Departments of Dermatology, Hospital Universitario San Carlos (Drs Sánchez-Yus and del Río), Fundación Jimenéz Díaz (Dr Requena), Hospital de Conxo, Santiago de Compostela (Dr Vázquez), and the Department of Cellular Biology, Facultad de Medicina, Universidad Complutense (Dr Simón), Madrid, Spain.

Arch Dermatol. 1997;133(6):743-745. doi:10.1001/archderm.1997.03890420081009

Objective:  To determine the distinction between a comedo and an infundibular cyst of Favre-Racouchot disease.

Setting:  A university hospital.

Patients:  From the 8 patients included in the study, 19 cysts and comedones were evaluated.

Main Outcome Measure:  The distinguishing features between the cysts and comedones of Favre-Racouchot disease.

Results:  All lesions were histologically indistinguishable from the primary comedones of acne vulgaris, except for the presence of a marked actinic elastosis in the surrounding dermis. The presence of a variable number of hair shafts and an abundant amount of bacteria, which was positive in the results of Gram staining and periodic acid-Schiff reaction and intermingled with sebum and eosinophilic laminated horny material within the dilated infundibulum, characterizes a comedo and differentiates it from an infundibular cyst.

Conclusions:  The cysts and comedones of Favre-Racouchot disease are closed and open comedones. They can be easily differentiated from an infundibular cyst by the histopathologic features rather than by the connection to the surface.Arch Dermatol. 1997;133:743-745