REPORT OF A CASE
A maculopapular eruption appeared on the trunk of a 2½-year-old boy after he had been treated with penicillin for tonsillopharyngitis. The rash progressed even though the penicillin therapy was discontinued. Vesicobullous lesions subsequently developed on the patient's face, trunk, and extremities and then spread to his scalp, soles, palms, and oral mucous membranes (Figure 1 and Figure 2). Physical examination revealed tense blisters of various size arising on an erythematous base. In some places, new vesicles were seen around older, crusted erosions (Figure 3). Nikolsky sign was absent. The complete and differential blood cell counts and the IgE level were normal. A skin biopsy specimen was obtained (Figure 4).What is your diagnosis?Vesicobullous Lesions in a Child
Bullous pemphigoid (BP).
HISTOPATHOLOGIC FINDINGS AND CLINICAL COURSE
The diagnosis of bullous pemphigoid was established by histologic examination and immunofluorescence findings. Light microscopic examination of the biopsy
Nyul Z, Harangi F, Várszegi D, Zombai E. Vesicobullous Lesions in a Child. Arch Dermatol. 1997;133(6):779–780. doi:10.1001/archderm.1997.03890420121018
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