No database for determination of precise risk of drug use during pregnancy and lactation is available. There are, however, educated opinions concerning the advisability of use of a drug during the childbearing years from manufacturers, the Food and Drug Administration, various teratologists, the American Academy of Pediatrics, and the World Health Organization. Not all medications are absolutely contraindicated during pregnancy and lactation. Some drugs have been extensively used without apparent adverse effects in the mother or infant. When it is necessary to select a medication for use during pregnancy or lactation, the medication should have minimal risk. This article summarizes dermatologic drugs whose known risk is low.
Arch Dermatol. 1997;133:894-898