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July 1997

Pulsed Dye Laser Treatment of Angiolymphoid Hyperplasia With Eosinophilia Lesions

Author Affiliations

Department of Dermatology University of Rochester 601 Elmwood Ave, Box 697 Rochester, NY 14642

Arch Dermatol. 1997;133(7):920-921. doi:10.1001/archderm.1997.03890430142028

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an anomalous vascular proliferation that usually affects the head and neck region of young women1 and can be a cosmetic problem. Many therapies have been used to treat ALHE with limited success, including cessation of estrogen therapy, treatment with oral retinoids and pentoxifylline, chemotherapeutics, surgical excision, electrodesiccation, and cryosurgery.2-7 The mainstay of therapy currently includes treatment with topical, intralesional, and systemic corticosteroids.8 Carbon dioxide and argon lasers also have been used to treat ALHE; however, scarring has been reported.7,9

Report of a Case.  A 30-year-old white woman presented with multiple discrete erythematous to violaceous papules and nodules, localized to her right ear and scalp (Figure 1). The patient was otherwise healthy. Her peripheral eosinophil count was slightly elevated at 1.2×106/L (normal range, 0-0.648×106/L). Histological study of a lesional biopsy specimen revealed an inflammatory infiltrate dominated by