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Sybert hits on an important factor for nevus development that was not carefully enough considered in our study. Additionally, it undoubtedly would be a doubly herculean work to count the nevi not only in children but also in their parents. Future studies, however, should take the numbers of nevi of the parents into consideration because this might be an additional important risk factor for the development of nevi in children.
Concerning the second issue, we reevaluated our data. Introducing the number of nevi at first visit into our logistic model, we found that this was the factor predicting the increase of melanocytic nevus counts with the highest significance (P<.001). Additionally, variables regarding sun exposure were still significantly related to the increase in the number of melanocytic nevi (Table) The skin type, however, was no longer a significant factor if the number of melanocytic nevi at first examination of the children
Luther H, Garbe C, Altmeyer P. Development of Melanocytic Nevi in Children-Reply. Arch Dermatol. 1997;133(8):1049. doi:10.1001/archderm.1997.03890440133023
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