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September 1997

Tufted Angioma Associated With Platelet Trapping Syndrome: Response to Aspirin

Author Affiliations

Pediatric Dermatology Unit and Pathology Department, Hôpital Pellegrin, Bordeaux, France

Arch Dermatol. 1997;133(9):1077-1079. doi:10.1001/archderm.1997.03890450015001

REPORT OF A CASE  A 3-month-old female infant presented with a vascular lesion that appeared on the left side of her neck and upper thorax at birth. Although relatively quiescent during the first 2 months of life, the lesion subsequently expanded significantly with a modification in color (Figure 1), and the infant was admitted to the hospital with a diagnosis of platelet trapping syndrome. This part of the observation has already been published.1 The hemangioma was inflammatory and ecchymotic, the platelet count was 34×109/L, and there was evidence of cardiac failure. Findings of a chest radiograph showed complete opacity of the left field, and results of a 2-dimensional echocardiogram revealed a massive pericardial effusion without extension of the vascular lesion to the heart. Platelet transfusions and repeated pericardial aspirations were ineffective in controlling clinical symptoms and increasing platelet counts. Treatment with aspirin and ticlopidine hydrochloride (10 mg/kg per