REPORT OF A CASE
A 30-year-old man presented with a 1.5-year history of intermittent skin lesions. The lesions were painful, under-went spontaneous ulceration, and resolved with scar formation over a 4-to 5-week period. His left arm was affected initially, but the lesions progressed to involve his chest, right arm, hands, and upper thigh area (Figure 1 and Figure 2). His medical history included a congenital retinoblastoma that had been surgically removed in infancy. Physical examination demonstrated numerous 0.5- to 1.2-cm erythematous papules, some with central necrosis. There was no lymphadenopathy or hepatosplenomegaly. The results of the following laboratory studies were normal: complete blood cell count, liver function tests, chemistry profile, and VDRL.A biopsy specimen was obtained from one of the papules, and representative features are seen in Figure 3 and Figure 4. Immunoperoxidase staining with CD45RO and CD30 antibodies is shown in Figure 5.What is your
Fretzin MH, Fretzin S, Fretzin D. A Papulonecrotic Eruption in a Young Man. Arch Dermatol. 1997;133(11):1453–1454. doi:10.1001/archderm.1997.03890470131021
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: