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March> 1, 2008

An Unusual Case of Leg Ulceration—Diagnosis

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Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2008

Arch Dermatol. 2008;144(3):405-410. doi:10.1001/archderm.144.3.dof70020-e

Findings from skin biopsy samples demonstrated occlusion of dermal blood vessels by eosinophilic thrombi with no evidence of vasculitis. There was necrosis of the overlying epidermis (Figure 3). Material that stained positive for periodic acid–Schiff stain was found deposited within the blood vessels. These findings were present on 4 separate biopsy samples. Test results for cryofibrinogen were positive.