I read with some interest the recent Off-Center Fold “Giant Subcutaneous Tumors on the Thighs” by Bae and colleagues,1 published in a recent issue of the Archives. Regrettably, Bae and coworkers appear to have missed the clinical and pathologic significance of the giant thigh masses in their patient. Based on the clinical history, the provided clinical photograph, and the photomicrographs, these “tumors” would appear to be indisputable examples of massive localized lymphedema of the morbidly obese, a distinctive pseudoneoplasm first reported by Farshid and Weiss2 in TheAmerican Journal of Surgical Pathology in 1998 and subsequently reported in a number of additional publications.3-12
Folpe AL. Giant Subcutaneous Tumors on the Thighs. Arch Dermatol. 2009;145(5):600. doi:10.1001/archdermatol.2009.64
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