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Evidence-Based Dermatology: Research Commentary
June 2009

Adalimumab vs Methotrexate for the Treatment of Chronic Plaque Psoriasis

Author Affiliations

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Dermatol. 2009;145(6):704-706. doi:10.1001/archdermatol.2009.104

Commentary on: Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)

Saurat JH, Stingl G, Dubertret L, et al

Br J Dermatol. 2008;158(3):558-566

Question: How effective and safe is adalimumab compared with methotrexate in patients with moderate to severe psoriasis?

Design: Noninferiority randomized controlled trial.

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